NIOSH Pocket Guide to Chemical Hazards

Rotenone CAS 83-79-4
C23H22O6 RTECS DJ2800000
Synonyms & Trade Names
1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methyl-ethenyl)-[1]benzopyrano [3,4-b]furo[2,3-h][1] benzopyran-6(6aH)-one
DOT ID & Guide
Exposure
Limits
NIOSH REL: TWA 5 mg/m3
OSHA PEL: TWA 5 mg/m3
IDLH 2500 mg/m3 Conversion
Physical Description
Colorless to red, odorless, crystalline solid. [insecticide]
MW: 394.4
BP: Decomposes
MLT: 330°F
Sol: Insoluble
VP: <0.00004 mmHg
IP: ?

Sp.Gr: 1.27
Fl.P: ?
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers, alkalis
Measurement Methods
NIOSH 5007
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA
Up to 50 mg/m3: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s) in combination with a dust, mist, and fume filter/(APF = 10) Any supplied-air respirator
Up to 125 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s) in combination with a dust, mist, and fume filter
Up to 250 mg/m3: (APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s) in combination with a high-efficiency particulate filter/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s) in combination with a high-efficiency particulate filter/(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Up to 2500 mg/m3: (APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, respiratory system; numb mucous membrane; nausea, vomiting, abdominal pain; muscle tremor, incoordination, clonic convulsions, stupor
Target Organs Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION